Two classic papers in acid-base physiology: contributions of R. F. Pitts, R. S. Alexander, and W. D. Lotspeich.

The Main Charge of the Kidney

This essay looks at the historical significance of two APS classic papers that are freely available online: Pitts RF and Alexander RS. The nature of the renal tubular mechanism for acidifying the urine. Am J Physiol 144: 239–254, 1945 (http://ajplegacy.physiology. org/cgi/reprint/144/2/239). Pitts RF and Lotspeich WD. Bicarbonate and the renal regulation of acid base balance. Am J Physiol 147: ...

The Renal Regulation of Acid-base Balance in Man. Ii. Factors Affecting the Excretion of Titratable Acid by the Normal Human Subject.

Solis Graphs and Uniquely Metric Basis Graphs

A set $Wsubset V (G)$ is called a resolving set, if for every two distinct vertices $u, v in V (G)$ there exists $win W$ such that $d(u,w) not = d(v,w)$, where $d(x, y)$ is the distance between the vertices $x$ and $y$. A resolving set for $G$ with minimum cardinality is called a metric basis. A graph with a unique metric basis is called a uniquely dimensional graph. In this paper, we establish...

Determination of Tocopherols and Fatty Acids in Seeds of

  Background: The dried fruits of Silybum marianum (L.) Gaertn (Compositae) contain silymarin, an isomeric mixture of flavonolignans. Silymarin acts as a strong anti -hepatotoxic. This fruits contains a high amount of oil .  Objective: The objective of this study was to determine total lipid content, fatty acid composition and content of different kind of tocopherols in seed oils of S. marianum...

Gallic acid protects the liver in rats against injuries induced by transient ischemia-reperfusion through regulating microRNAs expressions

Objective(s): Gallic acid (GA) is a highly effective antioxidant, which its beneficial effects are well known, but its impact on expression of microRNAs (miRs) following hepatic ischemia-reperfusion (I/R) is not well recognized. Therefore, the current research was designed to specify the beneficial effect of GA on miRs (122 and 34a), liver functional tests, and histopathological alterations bey...